VT-105 (VT105)

Chemical Structure : VT-105

CAS No.: 2417718-38-6

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货号: PC-49540Not For Human Use, Lab Use Only.

VT-105 (VT105) is a highly potent and selective TEAD inhibitor, selectively inhibit YAP/TAZ-TEAD promoted gene transcription with IC50 of 10.4 nM in YAP reporter assays, blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD.

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10 mg	￥3980	In stock
25 mg	￥5980	In stock
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100 mg		Get quote

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VT-105 (VT105) is a highly potent and selective TEAD inhibitor, selectively inhibits YAP/TAZ-TEAD promoted gene transcription with IC50 of 10.4 nM in YAP reporter assays.
VT-105 blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD.

物理化学性质&存储条件

分子量	421.42
分子式	C24H18F3N3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(1S)-1-(2-Pyridinyl)ethyl]-8-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide

参考文献

1. Tracy T Tang, et al. Mol Cancer Ther. 2021 Jun;20(6):986-998.

VT-105 (VT105)

生物&药学活性

物理化学性质&存储条件

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VT-105 (VT105)

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物理化学性质&存储条件

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