VRK1 inhibitor Compound 1 | VRK1 inhibitor | Probechem Biochemicals

Chemical Structure : VRK1 inhibitor Compound 1

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VRK1 inhibitor Compound 1 (VRK1-IN-1)

货号: PC-26316Not For Human Use, Lab Use Only.

VRK1 inhibitor Compound 1 (VRK1-IN-1) is a potent, selective and ATP-competitive inhibitor of Vaccinia-related kinase 1 (VRK1) with Ki of 82 nM and IC50 of 154 nM, selective for VRK1 over VRK2.

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生物&药学活性

VRK1 inhibitor Compound 1 (VRK1-IN-1) is a potent, selective and ATP-competitive inhibitor of Vaccinia-related kinase 1 (VRK1) with Ki of 82 nM and IC50 of 154 nM, selective for VRK1 over VRK2.

物理化学性质&存储条件

分子量	346.22
分子式	C14H13Cl2NO3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-3-butyl-5-(3,5-dichloro-4-hydroxybenzylidene)thiazolidine-2,4-dione

参考文献

1. Crowley-Dolen EK, et al. J Biol Chem. 2026 Mar 6:111355.

VRK1 inhibitor Compound 1 (VRK1-IN-1)

生物&药学活性

物理化学性质&存储条件

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VRK1 inhibitor Compound 1 (VRK1-IN-1)

生物&药学活性

物理化学性质&存储条件

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