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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-VP1.15
VP1.15

Chemical Structure : VP1.15

CAS No.: 1337960-51-6

VP1.15

货号: PC-23485Not For Human Use, Lab Use Only.

VP1.15 is a potent, dual PDE7/GSK-3 inhibitor with IC50 of 1.1 (PDE7) and 1.95 uM (GSK-3), shows antipsychotic and cognitive capacities.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VP1.15 is a potent, dual PDE7/GSK-3 inhibitor with IC50 of 1.1 (PDE7) and 1.95 uM (GSK-3), shows antipsychotic and cognitive capacities.

    物理化学性质&存储条件

    分子量 378.29
    分子式 C16H16BrN3OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-[(2,3-Diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)amino]ethanol hydrobromide

    参考文献

    1. Lipina TV, et al. Neuropharmacology. 2013 Jan;64:205-14.

    2. Paterniti I, et al. PLoS One. 2011 Jan 31;6(1):e15937.

    3. Medina-Rodríguez EM, et al. Sci Rep. 2017 Mar 3;7:43545.

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