VK4-116 | D3R antagonist | Probechem Biochemicals

Chemical Structure : VK4-116

加入收藏

VK4-116 (VK04-116)

货号: PC-35905Not For Human Use, Lab Use Only.

VK4-116 (VK04-116) is a novel potent, highly selective dopamine D3 receptor (D3R) antagonist with Ki of 6.8 nM, displays >1,000-fold selectivity over D2R.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

VK4-116 (VK04-116) is a novel potent, highly selective dopamine D3 receptor (D3R) antagonist with Ki of 6.8 nM, displays >1,000-fold selectivity over D2R.
VK4-116 inhibits oxycodone-induced hyperlocomotion in mice and reduces oxycodone-induced locomotor sensitization.
VK4-116 also dose-dependently inhibites the acquisition of oxycodone-induced conditioned place preference (CPP) in rats.

物理化学性质&存储条件

分子量	485.025
分子式	C26H33ClN4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(4-(3-Chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl)-3-hydroxybutyl)-1Hindole-2-carboxamide

参考文献

1. You ZB, et al. Neuropsychopharmacology. 2018 Nov 27. doi: 10.1038/s41386-018-0284-5.

2. Kumar V, et al. J Med Chem. 2016 Aug 25;59(16):7634-50.

VK4-116 (VK04-116)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

VK4-116 (VK04-116)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.