VK-28 | Iron chelator | Probechem Biochemicals

Chemical Structure : VK-28

CAS No.: 312611-92-0

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VK-28 (Iron chelator)

货号: PC-38601Not For Human Use, Lab Use Only.

VK-28 is a novel brain permeable neuroprotective iron chelator with anti-Alzheimer's disease activities, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation with IC50 of 12.7 uM.

规格	价格	库存
1 mg	￥1280	In stock
5 mg	￥2580	In stock
10 mg	￥4280	In stock
25 mg		Get quote

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生物&药学活性

VK-28 is a novel brain permeable neuroprotective iron chelator with anti-Alzheimer's disease activities, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation with IC50 of 12.7 uM.

物理化学性质&存储条件

分子量	287.363
分子式	C16H21N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[4-(2-Hydroxyethyl)piperazine-1-ylmethyl]-quinoline-8-ol

参考文献

1. Zhu W, et al. FASEB J. 2007 Dec;21(14):3835-44.

2. Bandyopadhyay S, et al. J Neural Transm Suppl. 2006;(71):237-47.

3. Weinreb O, et al. Neurotherapeutics. 2009 Jan;6(1):163-74.

4. Moussa B H Youdim, et al. Mech Ageing Dev. 2005 Feb;126(2):317-26.

VK-28 (Iron chelator)

生物&药学活性

物理化学性质&存储条件

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VK-28 (Iron chelator)

生物&药学活性

物理化学性质&存储条件

参考文献

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