VDAC inhibitor SC18

Chemical Structure : VDAC inhibitor SC18

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货号: PC-38524Not For Human Use, Lab Use Only.

VDAC inhibitor SC18 is a specific small molecule targeting the NADH-binding pocket of voltage dependent anion channels (VDAC), decreases mitochondrial membrane potential ΔΨm in HepG2 cells (EC50=25 uM), modulates mitochondrial metabolism in cancer cells, inhibit cell proliferation and induce cell death.

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250 mg		Get quote

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VDAC inhibitor SC18 is a specific small molecule targeting the NADH-binding pocket of voltage dependent anion channels (VDAC), decreases mitochondrial membrane potential ΔΨm in HepG2 cells (EC50=25 uM), modulates mitochondrial metabolism in cancer cells, inhibit cell proliferation and induce cell death.

物理化学性质&存储条件

分子量	385.683
分子式	C15H7ClF3N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-chloro-5-(trifluoromethyl)phenyl)-6-nitroquinazoline-2,4(1H,3H)-dione

参考文献

1. Heslop KA, et al. Biomed Pharmacother. 2022 Apr 18;150:112928.