Chemical Structure : Utomilumab
CAS No.: 1417318-27-4
货号: PC-Ab1040Not For Human Use, Lab Use Only.
Utomilumab (PF-05082566) is a ligand-blocking antibody, binds 4-1BB between CRDs 3 and 4, a fully human monoclonal antibody (mAb) agonist that selectively binds to 4-1BB (also called CD137), a protein receptor expressed in many cancer-fighting T cells. Utomilumab (PF-05082566) binds specifically to 4-1BB (CD-137), a receptor protein found in many immune cells, such as T-cells (killer T-cells and helper T-cells) and natural killer cells..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Utomilumab (PF-05082566) is a ligand-blocking antibody, binds 4-1BB between CRDs 3 and 4, a fully human monoclonal antibody (mAb) agonist that selectively binds to 4-1BB (also called CD137), a protein receptor expressed in many cancer-fighting T cells. Utomilumab (PF-05082566) binds specifically to 4-1BB (CD-137), a receptor protein found in many immune cells, such as T-cells (killer T-cells and helper T-cells) and natural killer cells.
分子量 | ||
分子式 | Human IgG2-Lambda 2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Utomilumab; PF-05082566; PF 05082566; 1417318-27-4; 4-1BB/CD137 antibody; 4-1BB/CD137; CD137 antigen agonists; PF-2566; PF-5082566 |
1. 1, Chin SM, et al. Nat Commun. 2018 Nov 8;9(1):4679. 2, Segal NH, et al. Clin Cancer Res. 2018 Apr 15;24(8):1816-1823. 3, Tolcher AW, et al. Clin Cancer Res. 2017 Sep 15;23(18):5349-5357. 4, Fisher TS, et al. Cancer Immunol Immunother. 2012 Oct;61(10):1721-33.
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