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首页-小分子抑制剂&激动剂-Autophagy-Mitophagy-Urolithin A
Urolithin A

Chemical Structure : Urolithin A

CAS No.: 1143-70-0

Urolithin A

货号: PC-42209Not For Human Use, Lab Use Only.

Urolithin A is a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption.

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25 mg ¥1980 In stock
100 mg ¥4980 In stock
200 mg Get quote
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纯度 & COA & 质检文件 纯度: 99.13% (HPLC) Select Batch:

生物&药学活性

Urolithin A is a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption.
Urolithin A prevents the accumulation of dysfunctional mitochondria with age and extends lifespan in C. elegans.
Urolithin A improves exercise capacity in mouse models of age-related decline of muscle function.

物理化学性质&存储条件

分子量 228.2002
分子式 C13H8O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 33 mg/mL

Chemical Name/SMILES

6H-Dibenzo[b,d]pyran-6-one, 3,8-dihydroxy-

参考文献

1. Ryu D, et al. Nat Med. 2016 Aug;22(8):879-88.

2. Tang L, et al. Biochem Biophys Res Commun. 2017 May 6;486(3):774-780.

3. Guada M, et al. J Pharmacol Exp Ther. 2017 Oct;363(1):58-65.

4. Zhao W, et al. Mol Carcinog. 2017 Oct 4.

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