Chemical Structure : Urelumab
CAS No.: 934823-49-1
货号: PC-Ab1012Not For Human Use, Lab Use Only.
Urelumab is an agonist antibody to CD137 with potential application as an immuno-oncology therapeutic, enhances NK-cell activation increasing CD25 expression and IFNɣ production, but not in vitro ADCC. Urelumab enhances T-cell and natural killer-cell antitumor activity in preclinical models, and may enhance cytotoxic activity of rituximab..
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Urelumab is an agonist antibody to CD137 with potential application as an immuno-oncology therapeutic, enhances NK-cell activation increasing CD25 expression and IFNɣ production, but not in vitro ADCC. Urelumab enhances T-cell and natural killer-cell antitumor activity in preclinical models, and may enhance cytotoxic activity of rituximab.
分子量 | ||
分子式 | Human IgG4P-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Urelumab; BMS-663513; Anti-4-1BB antibody; CD137; Anti-human 4-1BB; TNFRSF9 |
1. 1, Srivastava RM, et al. Clin Cancer Res. 2017 Feb 1;23(3):707-716. 2, Ho SK, et al. Mol Cancer Ther. 2020 Apr;19(4):1040-1051. 3, Cabo M, et al. Cancer Immunol Res. 2021 Sep 27. doi: 10.1158/2326-6066.CIR-21-0030. 4, Harao M, et al. Cancer Immunol Res. 2017 Jun;5(6):439-445.
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