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首页-小分子抑制剂&激动剂-GPCR-Trace Amine-associated Receptor (TAAR)-Ulotaront
Ulotaront

Chemical Structure : Ulotaront

CAS No.: 1310426-33-5

Ulotaront (SEP-363856, SEP-856)

货号: PC-72627Not For Human Use, Lab Use Only.

Ulotaront (SEP-363856, SEP-856) is a novel psychotropic agent with agonism at trace amine receptor 1 (TAAR1) and 5-HT1A receptors but no appreciable action at dopamine D2 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Ulotaront (SEP-363856, SEP-856) is a novel psychotropic agent with agonism at trace amine receptor 1 (TAAR1) and 5-HT1A receptors but no appreciable action at dopamine D2 receptors.
    Ulotaront significantly reduced the ketamine-induced increase in dopamine synthesis capacity.

    物理化学性质&存储条件

    分子量 183.269
    分子式 C9H13NOS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-[(7S)-5,7-dihydro-4H-thieno[2,3-c]pyran-7-yl]-N-methylmethanamine

    参考文献

    1. Dedic N, et al. J Pharmacol Exp Ther. 2019 Oct;371(1):1-14.

    2. Koblan KS, et al. N Engl J Med. 2020 Apr 16;382(16):1497-1506.

    3. Mol Psychiatry. 2021 Aug 10. doi: 10.1038/s41380-021-01250-7.

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