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UbV SP.3

Chemical Structure : UbV SP.3

CAS No.:

UbV SP.3 (ALKLG GKITR IARTP QHETH VLRHF RVSM)

货号: PC-72761Not For Human Use, Lab Use Only.

UbV SP.3 is potent, selective inhibitor of STAMBP isopeptidase activity with KD/IC50 of 60/9.8 nM, with significant preferential binding to STAMBP over STAMBPL1 (250 -fold selectivity).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UbV SP.3 is potent, selective inhibitor of STAMBP isopeptidase activity with KD/IC50 of 60/9.8 nM, with significant preferential binding to STAMBP over STAMBPL1 (250 -fold selectivity).
UbV SP.3 bind both the full-length and the JAMM domain of STAMBP (STAMBPJAMM), far exceeding the reported small-molecule inhibitor BC-1471.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

参考文献

1. Yusong Guo, et al. J Biol Chem. 2021 Oct; 297(4): 101107.

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