UVI-3003 |CAS:847239-17-2 Probechem Biochemicals

Chemical Structure : UVI-3003

CAS No.: 847239-17-2

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UVI-3003 (UVI3003;UVI 3003)

货号: PC-70298Not For Human Use, Lab Use Only.

UVI-3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.

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10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

UVI-3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
UVI-3003 does not affect the corepressor interaction capacity of the RARα subunit in the RAR-RXR heterodimer configuration.

物理化学性质&存储条件

分子量	436.6
分子式	C28H36O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid

参考文献

1. Habchi J, et al. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208.

2. Nahoum V, et al. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8.

UVI-3003 (UVI3003;UVI 3003)

生物&药学活性

物理化学性质&存储条件

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UVI-3003 (UVI3003;UVI 3003)

生物&药学活性

物理化学性质&存储条件

参考文献

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