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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Beta-catenin-UU-T01
UU-T01

Chemical Structure : UU-T01

CAS No.: 1417162-83-4

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UU-T01 (UU-T 01)

货号: PC-61799Not For Human Use, Lab Use Only.

UU-T01 is a novel small-molecule inhibitor of β-catenin/Tcf4 protein-protein interaction with Ki of 3.14 uM, binds to β-catenin with Kd of 0.531 uM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    UU-T01 is a novel small-molecule inhibitor of β-catenin/Tcf4 protein-protein interaction with Ki of 3.14 uM, binds to β-catenin with Kd of 0.531 uM.

    物理化学性质&存储条件

    分子量 230.231
    分子式 C10H10N6O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-(2-(2H-tetrazol-5-yl)ethyl)-1H-indazol-1-ol

    参考文献

    1. Yu B, et al. ACS Chem Biol. 2013 Mar 15;8(3):524-9.

    2. Yan M, et al. Exp Biol Med (Maywood). 2017 Jun;242(11):1185-1197.

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