UTL-5g |CAS:646530-37-2 Probechem Biochemicals

Chemical Structure : UTL-5g

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UTL-5g (GBL-5g)

货号: PC-61792Not For Human Use, Lab Use Only.

UTL-5g (GBL-5g) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity.

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生物&药学活性

UTL-5g (GBL-5g) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity; lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice; a novel chemo- and radioprotective agent.

物理化学性质&存储条件

分子量	271.097
分子式	C11H8Cl2N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,4-dichlorophenyl)-5-methylisoxazole-3-carboxamide

参考文献

1. Shaw J, et al. J Exp Ther Oncol. 2011;9(2):129-37.

2. Shaw J, et al. Cancer Chemother Pharmacol. 2013 Sep;72(3):703-7.

3. Carruthers NJ, et al. Eur J Pharmacol. 2017 Sep 15;811:66-73.

UTL-5g (GBL-5g)

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UTL-5g (GBL-5g)

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