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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-USP7-IN-1
USP7-IN-1

Chemical Structure : USP7-IN-1

CAS No.: 1381291-36-6

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USP7-IN-1

货号: PC-45056Not For Human Use, Lab Use Only.

USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM.

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5 mg ￥2680 In stock
10 mg ￥4280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM.
USP7-IN-1 shows less or no inhibition on USP5, USP8, Uch-L1, Uch-L3 and Caspase (IC50>200 uM).
USP7-IN-1 inhibits HCT116 cell viability with GI50 of 67 uM.

物理化学性质&存储条件

分子量 425.908
分子式 C23H24ClN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL
Chemical Name/SMILES

4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-

参考文献

1. Patent. WO 2013030218 A1 20130307.

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