USP7-866 | USP7 inhibitor | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-USP7-866

Chemical Structure : USP7-866

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USP7-866 (USP 7-866)

货号: PC-38192Not For Human Use, Lab Use Only.

USP7-866 is a novel potent selective inhibitor of USP7 with IC50 of 0.18 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

USP7-866 is a novel potent selective inhibitor of USP7 with IC50 of 0.18 nM.
USP7-866 inhibited the growth of p53-mutant small cell lung cancer cell line H526 at a CC50 of 42 nM.

物理化学性质&存储条件

分子量	524.076
分子式	C28H30ClN3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((7-(5-chloro-3-methyl-2-(((3S,4R)-3-methylpiperidin-4-yl)oxy)phenyl)thieno[3,2-b]pyridin-2-yl)methyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione

参考文献

1. Yamini M Ohol, et al. Mol Cancer Ther. 2020 Oct;19(10):1970-1980.

2. Paul R Leger, et al. J Med Chem. 2020 May 28;63(10):5398-5420.

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USP7-866 (USP 7-866)

生物&药学活性

物理化学性质&存储条件

参考文献

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USP7-866 (USP 7-866)

生物&药学活性

物理化学性质&存储条件

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