Chemical Structure : USP5-Cav3.2 inhibitor II-1
货号: PC-72884Not For Human Use, Lab Use Only.
USP5-Cav3.2 inhibitor II-1 is a small molecule inhibitor of USP5-Cav3.2 interaction, without affecting the enzymatic activity of USP5.
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USP5-Cav3.2 inhibitor II-1 is a small molecule inhibitor of USP5-Cav3.2 interaction, without affecting the enzymatic activity of USP5.
II-1 inhibited both phases of formalin-induced nocifensive behaviors in mice.
Cav3.2 is required for the action of II-1.
II-1 also mediated a robust inhibition of mechanical allodynia induced by injury to the sciatic nerve.
分子量 | 264.31 | |
分子式 | C8H12N2O4S2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Garcia-Caballero A, et al. ACS Chem Neurosci. 2022 Feb 16;13(4):524-536.
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