USP3 inhibitor 59

Chemical Structure : USP3 inhibitor 59

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货号: PC-21559Not For Human Use, Lab Use Only.

USP3 inhibitor 59 is a relatively specific small molecule chemical handle with SPR value of 14 uM, binds to zinc-finger ubiquitin binding domain (ZnF-UBD).

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

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生物&药学活性

USP3 inhibitor 59 is a relatively specific small molecule chemical handle with SPR value of 14 uM, binds to zinc-finger ubiquitin binding domain (ZnF-UBD).
USP3 inhibitor 59 displays 5-times selective for USP3 over USP5, USP16, and HDAC6 ZnF-UBDs.
USP3 inhibitor 59 does not inhibit USP3 catalytic activity.
USP3 inhibitor 59 could be used to interrogate the function of the USP3 Znf-UBD and the consequences of recruiting USP3 to ubiquitylated proteins.

物理化学性质&存储条件

分子量	373.38
分子式	C17H15N3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-(1H-pyrrolo[2,3-b]pyridine-3-sulfonamido)phenyl)-4-oxobutanoic acid

参考文献

1. Mandeep K. Mann, et al. ACS Omega 2023.