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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-USL311
USL311

Chemical Structure : USL311

CAS No.: 1373268-67-7

USL311 (USL-311)

货号: PC-73171Not For Human Use, Lab Use Only.

USL311 is a potent, selective, orally bioavailable CXCR4 antagonist, with potential antineoplastic activity.

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10 mg ¥2280 In stock
25 mg ¥3980 In stock
50 mg ¥6580 In stock
100 mg ¥9880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

USL311 is a potent, selective, orally bioavailable CXCR4 antagonist, with potential antineoplastic activity.
USL311 binds to CXCR4, prevente the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4 and inhibiting CXCR4 activation, decreases proliferation and migration of CXCR4-expressing tumor cells.
CXCR4, a chemokine receptor belonging to the G protein-coupled receptor (GPCR) family, plays an important role in chemotaxis and angiogenesis, and is upregulated in several tumor cell types.

物理化学性质&存储条件

分子量 422.577
分子式 C24H34N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

参考文献

1. Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1

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