欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-PARP-UPF-1069
UPF-1069

Chemical Structure : UPF-1069

CAS No.: 1048371-03-4

加入收藏

UPF-1069 (UPF1069)

货号: PC-23463Not For Human Use, Lab Use Only.

UPF-1069 is a potent, selective PARP-2 inhibitor with IC50 of 0.3 uM, >25-fold selective over PARP-1 (IC50= 8 uM).

规格 价格 库存 数量
10 mg ￥580 In stock
25 mg ￥980 In stock
50 mg ￥1580 In stock
100 mg ￥2480 In stock
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UPF-1069 is a potent, selective PARP-2 inhibitor with IC50 of 0.3 uM, >25-fold selective over PARP-1 (IC50= 8 uM).
UPF-1069 does not interact with other PARP family member enzymes (including tankyrase-1).
UPF-1069 reduced post-ischaemic damage at both low and high concentrations in mixed cortical cells exposed to oxygen-glucose deprivation (OGD).
UPF-1069 exacerbates OGD toxicity in hippocampal CA1 pyramids and reduces it in cortical neurons.

物理化学性质&存储条件

分子量 279.30
分子式 C17H13NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(2-Oxo-2-phenylethoxy)isoquinolin-1(2H)-one

参考文献

1. Moroni F, et al. Br J Pharmacol. 2009 Jul;157(5):854-62.

2. Pellicciari R, et al. ChemMedChem. 2008;3:914–923.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: