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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-UNC7242
UNC7242

Chemical Structure : UNC7242

CAS No.:

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UNC7242 (UNC-7242)

货号: PC-26589Not For Human Use, Lab Use Only.

UNC7242 is a small molecule antagonist of PRC2 components PHF1 and PHF19 with ITC Kd of 1.13 uM and 0.64 uM, displaces recombinant or endogenous PHF1 or 19 from nucleosomes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UNC7242 is a small molecule antagonist of PRC2 components PHF1 and PHF19 with ITC Kd of 1.13 uM and 0.64 uM, displaces recombinant or endogenous PHF1 or 19 from nucleosomes.

物理化学性质&存储条件

分子量 376.89
分子式 C19H25ClN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-chloro-4-(4-(cyclopropylmethyl)-1,4-diazepan-1-yl)-6,7-dimethoxyquinazoline

参考文献

1. Amick IE, et al. ACS Bio Med Chem Au. 2026 Mar 2;6(2):101-117.

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