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首页-小分子抑制剂&激动剂-Tyrosine Kinase-TAM Receptor (Tyro3-Axl-Mer)-UNC2541
UNC2541

Chemical Structure : UNC2541

CAS No.: 1612782-86-1

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UNC2541 (UNC-2541)

货号: PC-23043Not For Human Use, Lab Use Only.

UNC2541 is a potent, specific Mer tyrosine kinase (MerTK) inhibitor with IC50 of 4.4 nM, >25-fold selective over Tyro3, Axl, and FLT3, shows EC50 of 550 nM in pMerTK ELISA assays.

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5 mg ￥780 In stock
10 mg ￥1180 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UNC2541 is a potent, specific Mer tyrosine kinase (MerTK) inhibitor with IC50 of 4.4 nM, >25-fold selective over Tyro3, Axl, and FLT3, shows EC50 of 550 nM in pMerTK ELISA assays.

物理化学性质&存储条件

分子量 471.58
分子式 C24H34FN7O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-7-Amino-N-(4-fluorobenzyl)-8-oxo-2,9,16,18,21-pentaazabicyclo[15.3.1]henicosa-1(20),16,18-triene-20-carboxamide

参考文献

1. Andrew L McIver, et al. ChemMedChem. 2017 Feb 3;12(3):207-213.

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