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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-UNC1215
UNC1215

Chemical Structure : UNC1215

CAS No.: 1415800-43-9

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UNC1215 (UNC 1215;UNC-1215)

货号: PC-44607Not For Human Use, Lab Use Only.

UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.
UNC1215 is 50-fold more potent toward L3MBTL3 than other members of the MBT family.
UNC1215 directly binds to L3MBTL3 via the Kme-binding pocket of the MBT domains.

物理化学性质&存储条件

分子量 529.7161
分子式 C32H43N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 270 mg/mL
Chemical Name/SMILES

Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]-

参考文献

1. James LI, et al. Nat Chem Biol. 2013 Mar;9(3):184-91.

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