UNC0224 | G9a/GLP inhibitor | Probechem Biochemicals

Chemical Structure : UNC0224

CAS No.: 1197196-48-7

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UNC0224 (UNC 0224, UNC-0224)

货号: PC-42740Not For Human Use, Lab Use Only.

UNC0224 (UNC-0224) is a potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM in biochemical assays.

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5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

UNC0224 (UNC-0224) is a potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM in biochemical assays.
UNC0224 dispalys >1000-fold selectivity for G9a over SET7/9, SET8, PRMT3 and JMJD2E (IC50>4 uM).

物理化学性质&存储条件

分子量	485.6653
分子式	C26H43N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Quinazolinamine, 7-[3-(dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-

参考文献

1. Liu F, et al. J Med Chem. 2010 Aug 12;53(15):5844-57.

2. Liu F, et al. J Med Chem. 2009 Dec 24;52(24):7950-3.

UNC0224 (UNC 0224, UNC-0224)

生物&药学活性

物理化学性质&存储条件

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UNC0224 (UNC 0224, UNC-0224)

生物&药学活性

物理化学性质&存储条件

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