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首页-小分子抑制剂&激动剂-Others-Other Targets-UNC-CA157
UNC-CA157

Chemical Structure : UNC-CA157

CAS No.: 2190517-67-8

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UNC-CA157

货号: PC-49413Not For Human Use, Lab Use Only.

UNC-CA157 is a selective small molecule inhibitor of the archetypal UbiB member COQ8A with IC50 of 580 nM, shows clear preference for COQ8A over COQ8B.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    UNC-CA157 is a selective small molecule inhibitor of the archetypal UbiB member COQ8A with IC50 of 580 nM, shows clear preference for COQ8A over COQ8B.
    UNC-CA157 (20 uM) decreases de novo CoQ production in COQ8BKO HAP1 cells.

    物理化学性质&存储条件

    分子量 335.363
    分子式 C19H17N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-((3,4,5-trimethoxyphenyl)amino)quinoline-7-carbonitrile

    参考文献

    1. Nathan H Murray, et al. Nat Chem Biol. 2022 Oct 27. doi: 10.1038/s41589-022-01168-3.

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