UNC-2170 |CAS:1648707-58-7 Probechem Biochemicals

Chemical Structure : UNC-2170

CAS No.: 1648707-58-7

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UNC-2170 (UNC2170)

货号: PC-62384Not For Human Use, Lab Use Only.

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.

规格	价格	库存
10 mg	￥1980	In stock
25 mg	￥2980	In stock
50 mg	￥4580	In stock
100 mg		Get quote

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生物&药学活性

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
UNC-2170 is highly cell permeant with no significant measureable cellular efflux.
UNC-2170 shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.

物理化学性质&存储条件

分子量	313.23
分子式	C14H21BrN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-bromo-N-(3-(tert-butylamino)propyl)benzamide

参考文献

1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.

UNC-2170 (UNC2170)

生物&药学活性

物理化学性质&存储条件

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UNC-2170 (UNC2170)

生物&药学活性

物理化学性质&存储条件

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