UMB-32 |CAS:1635437-39-6 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-UMB-32

Chemical Structure : UMB-32

加入收藏

UMB-32 (UMB 32;UMB32)

货号: PC-60389Not For Human Use, Lab Use Only.

UMB-32 is a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM.

规格	价格	库存	数量
5 mg		Get quote
10 mg		Get quote
25 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UMB-32 is a potent, selective inhibitor of BRD4 with Kd of 550 nM, cellular IC50 of 724 nM.
UMB-32 also potently binds to the TAF1 (560 nM) and TAF1L (1.3 uM) bromodomains.
UMB-32 significantly induces HIV-1 reactivation.

物理化学性质&存储条件

分子量	361.4
分子式	C21H23N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1,1-dimethylethyl)-2-[4-(3,5-dimethyl-4-isoxazolyl)phenyl]-imidazo[1,2-a]pyrazin-3-amine

参考文献

1. McKeown MR, et al. J Med Chem. 2014 Nov 13;57(21):9019-27.

2. Huang H, et al. Front Microbiol. 2017 Jun 7;8:1035.

联系我们 sales@probechem.com

UMB-32 (UMB 32;UMB32)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

UMB-32 (UMB 32;UMB32)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.