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首页-小分子抑制剂&激动剂-Others-Other Targets-UM-1098
UM-1098

Chemical Structure : UM-1098

CAS No.: 3118718-78-5

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UM-1098 (UM1098)

货号: PC-27718Not For Human Use, Lab Use Only.

UM-1098 is a synthetic macrophage-Inducible C-type Lectin (Mincle) agonist, induces Th17, Th1, Th2 polarizing innate cytokines in mouse PBMCs, induces strong Th1 and Th17 immunity after vaccination with Mtb antigens.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UM-1098 is a synthetic macrophage-Inducible C-type Lectin (Mincle) agonist, induces Th17, Th1, Th2 polarizing innate cytokines in mouse PBMCs, induces strong Th1 and Th17 immunity after vaccination with Mtb antigens.

物理化学性质&存储条件

分子量 1319.80
分子式 C74H126O19
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

((2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-oxybis(3,4,5-trihydroxytetrahydro-2H-pyran-6,2-diyl))bis(methylene) bis(3,4,5-tris(octyloxy)benzoate)

参考文献

1. Viktoria Rungelrath, et al. NPJ Vaccines. 2024 Jun 6;9(1):100.

2. Rungelrath V, et al. Vaccine X. 2025 Oct;26:100699.

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