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首页-小分子抑制剂&激动剂-GPCR-Protease-activated Receptor (PAR)-UDM-001651
UDM-001651

Chemical Structure : UDM-001651

CAS No.: 1477497-01-0

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UDM-001651 (UDM001651, UDM 001651)

货号: PC-73008Not For Human Use, Lab Use Only.

UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    UDM-001651 (UDM001651) is a potent, selective, and orally bioavailable PAR4 antagonist with IC50 of 2.4 nM.
    UDM-001651 demonstrated robust antithrombotic efficacy and no prolongation of kidney bleeding time in a monkey thrombosis model.

    物理化学性质&存储条件

    分子量 513.56
    分子式 C28H23N3O5S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(4-((3-(Benzyloxy)benzyl)oxy)-6-methoxybenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

    参考文献

    1. Miller MM, et al. J Med Chem. 2019 Jun 27. J Med Chem. 2019 Aug 22;62(16):7400-7416.

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