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首页-小分子抑制剂&激动剂-Others-Other Targets-UCP0054278
UCP0054278

Chemical Structure : UCP0054278

CAS No.: 52346-00-6

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UCP0054278 (DJ-1 inhibitor compound B)

货号: PC-22172Not For Human Use, Lab Use Only.

DJ-1 inhibitor comp-23 is a small molecule binding to DJ-1 (PARK7) with binding Kd of 1.33 uM, inhibits oxidative stress-induced cell death of human dopaminergic neuroblastoma cell line SH-SY5Y cells at 1 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DJ-1 inhibitor comp-23 is a small molecule binding to DJ-1 (PARK7) with binding Kd of 1.33 uM, inhibits oxidative stress-induced cell death of human dopaminergic neuroblastoma cell line SH-SY5Y cells at 1 uM.

物理化学性质&存储条件

分子量 449.50
分子式 C26H27NO6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(7-methoxybenzo[d][1,3]dioxol-5-yl)ethyl)acetamide

参考文献

1. Shin Miyazaki, et al. J Neurochem. 2008 Jun 1;105(6):2418-34.

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