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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-UCM05
UCM05

Chemical Structure : UCM05

CAS No.: 1094451-90-7

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UCM05 (G28UCM)

货号: PC-25151Not For Human Use, Lab Use Only.

UCM05 is a specfic small molecule inhibitor of bacterial cell division targeting the GTP-binding site of FtsZ with Kb of 43 uM, inhibits the growth of the Gram-positive bacterium B. subtilis with MIC of 100 uM, also is a fatty acid synthase (FASN) inhibitor wiht activity against HER2+ breast cancer.

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5 mg ￥780 In stock
10 mg ￥1180 In stock
25 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UCM05 is a specfic small molecule inhibitor of bacterial cell division targeting the GTP-binding site of FtsZ with Kb of 43 uM, inhibits the growth of the Gram-positive bacterium B. subtilis with MIC of 100 uM, also is a fatty acid synthase (FASN) inhibitor wiht activity against HER2+ breast cancer.

物理化学性质&存储条件

分子量 464.38
分子式 C24H16O10
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

naphthalene-1,3-diyl bis(3,4,5-trihydroxybenzoate)

参考文献

1. Ruiz-Avila LB, et al. ACS Chem Biol. 2013 Sep 20;8(9):2072-83.

2. Li S, et al. Virol J. 2025 Jul 19;22(1):249.

3. Teresa Puig, et al. Breast Cancer Res. 2011;13(6):R131.

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