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首页-小分子抑制剂&激动剂-Others-Other Targets-UCB1244283
UCB1244283

Chemical Structure : UCB1244283

CAS No.: 300587-89-7

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UCB1244283 (UCB-1244283)

货号: PC-25443Not For Human Use, Lab Use Only.

UCB1244283 is a selective allosteric modulator of synaptic vesicle protein 2A (SV2A), selective over SV2B and SV2C, enhances brivaracetam (BRV) binding by occupying an allosteric site near the primary binding site, preventing BRV dissociation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    UCB1244283 is a selective allosteric modulator of synaptic vesicle protein 2A (SV2A), selective over SV2B and SV2C, enhances brivaracetam (BRV) binding by occupying an allosteric site near the primary binding site, preventing BRV dissociation.

    物理化学性质&存储条件

    分子量 311.43
    分子式 C20H25NO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-(3,5-dimethylphenyl)-N-(2-methoxyphenyl)-3-methylbutanamide

    参考文献

    1. Mittal A, et al. Proc Natl Acad Sci U S A. 2025 Sep 9;122(36):e2510239122.

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