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首页-小分子抑制剂&激动剂-Apoptosis-TNF-alpha-UCB-5307
UCB-5307

Chemical Structure : UCB-5307

CAS No.: 1515887-44-1

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UCB-5307 (UCB5307)

货号: PC-49445Not For Human Use, Lab Use Only.

UCB-5307 is a small molecule compound inhibiting TNFR1 signalling and downstream function in vitro, bind directly to TNF with slow binding kinetics (KD= 6 nM).

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3580 In stock
50 mg ￥5580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

UCB-5307 is a small molecule compound inhibiting TNFR1 signalling and downstream function in vitro, bind directly to TNF with slow binding kinetics (KD= 6 nM).

物理化学性质&存储条件

分子量 343.42
分子式 C22H21N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-[(2,5-Dimethylphenyl)methyl]-α-4-pyridinyl-1H-benzimidazole-2-methanol

参考文献

1. James O'Connell, et al. Nat Commun. 2019 Dec 19;10(1):5795.

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