UBP 296 |CAS:745055-86-1 Probechem Biochemicals

Chemical Structure : UBP 296

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UBP 296 (UBP296;UBP-296)

货号: PC-60772Not For Human Use, Lab Use Only.

UBP 296 (UBP296, UBP-296) is a potent, and selective GluR5-subunit containing kainate receptor antagonist with Kd of 1.09 uM.

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1 g		Get quote

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生物&药学活性

UBP 296 (UBP296, UBP-296) is a potent, and selective GluR5-subunit containing kainate receptor antagonist with Kd of 1.09 uM; displays 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors, little or no action at NMDA or group I mGlu receptors; blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibers.

物理化学性质&存储条件

分子量	333.3
分子式	C15H15N3O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione

参考文献

1. Dolman NP, et al. J Med Chem. 2005 Dec 1;48(24):7867-81.

2. More JC, et al. Neuropharmacology. 2004 Jul;47(1):46-64.

3. Andreou AP, et al. Br J Pharmacol. 2009 Jun;157(3):464-73.

UBP 296 (UBP296;UBP-296)

生物&药学活性

物理化学性质&存储条件

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UBP 296 (UBP296;UBP-296)

生物&药学活性

物理化学性质&存储条件

参考文献

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