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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-UBP1700
UBP1700

Chemical Structure : UBP1700

CAS No.: 2550326-84-4

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UBP1700 (UBP 1700)

货号: PC-21032Not For Human Use, Lab Use Only.

UBP1700 is a subtype-selective competitive antagonist of GluN2C/2D-containing NMDA receptors with Ki of 7-9 nM, 50-fold selectivity over GluN2A and GluN2B.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

UBP1700 is a subtype-selective competitive antagonist of GluN2C/2D-containing NMDA receptors with Ki of 7-9 nM, 50-fold selectivity over GluN2A and GluN2B.
UBP1700 shows minimally act on non-NMDARs.

物理化学性质&存储条件

分子量 448.43
分子式 C24H20N2O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

O=C([C@@H]1N(C(C2=CC=C3C4=CC=C(/C=C/C(O)=O)C=C4C=CC3=C2)=O)CCN[C@@H]1C(O)=O)O

参考文献

1. Wang JX, et al. Nat Commun. 2020 Jan 22;11(1):423.

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