UBCS385 | Sirtuin 4 inhibitor | Probechem Biochemicals

Chemical Structure : UBCS385

加入收藏

UBCS385 (Sirt4 inhibitor 60)

货号: PC-21714Not For Human Use, Lab Use Only.

UBCS385 (Sirt4 inhibitor 60) is a potent, selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 0.9 uM.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

UBCS385 (Sirt4 inhibitor 60) is a potent, selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 0.9 uM.
UBCS385 displays weak effect on Sirt3 and high selectivity against Sirt1, −2, −5, and −6.
UBCS385 inhibits Sirt4 through binding to active site regions overlapping with the acyl-peptide binding regions but not with the NAD+ site.

物理化学性质&存储条件

分子量	586.05
分子式	C24H16ClN5O5S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((5-Chloro-1H-benzo[d]imidazole-2-yl)thio)-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)-2-phenylacetamide

参考文献

1. Martin Pannek, et al. J Med Chem. 2024 Jan 22. doi: 10.1021/acs.jmedchem.3c01496.

UBCS385 (Sirt4 inhibitor 60)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

UBCS385 (Sirt4 inhibitor 60)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.