UAMC-1110 (SP-13786) | FAP inhibitor | Probechem Biochemicals

Chemical Structure : UAMC-1110

CAS No.: 1448440-52-5

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UAMC-1110 (UAMC1110, SP-13786, SP13786)

货号: PC-36075Not For Human Use, Lab Use Only.

UAMC-1110 (SP-13786) is a potent, selective small molecule inhibitor of fibroblast activation protein (FAP) with IC50 of 3.2 nM.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
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100 mg		Get quote

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生物&药学活性

UAMC-1110 (SP-13786) is a potent, selective small molecule inhibitor of fibroblast activation protein (FAP) with IC50 of 3.2 nM.
UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with IC50 of 1.8 uM.

物理化学性质&存储条件

分子量	344.322
分子式	C17H14F2N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide

参考文献

1. Gunderson AJ, et al. PLoS One. 2019 Feb 6;14(2):e0211117.

2. Jansen K, et al. ACS Med Chem Lett. 2013 Mar 18;4(5):491-6.

3. Jansen K, et al. J Med Chem. 2014 Apr 10;57(7):3053-74.

UAMC-1110 (UAMC1110, SP-13786, SP13786)

生物&药学活性

物理化学性质&存储条件

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UAMC-1110 (UAMC1110, SP-13786, SP13786)

生物&药学活性

物理化学性质&存储条件

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