UAB126 |CAS:1854907-40-6 Probechem Biochemicals

Chemical Structure : UAB126

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UAB126 (UAB 126)

货号: PC-38132Not For Human Use, Lab Use Only.

UAB126 (UAB 126) is a novel rexinoid-like small molecule that show positive effects on metabolic syndrome without the known side effects of potent rexinoids.

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生物&药学活性

UAB126 (UAB 126) is a novel rexinoid-like small molecule that show positive effects on metabolic syndrome without the known side effects of potent rexinoids.
Oral administration of UAB126 prevents HFD-induced obesity and increases fatty acid oxidation.
UAB126 modulates genes that are involved in lipolysis and proinflammatory response in WAT, and prevents HFD-induced insulin resistance and HFD-induced hepatic steatosis and hyperlipidemia.
UAB126 modulates gene expression profiles involved in glucose and lipid metabolism.
UAB126 suppresses hepatic lipogenic genes, including Srebp-1c, Pparγ2, and Scd1.

物理化学性质&存储条件

分子量	274.319
分子式	C19H14O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 1 Month
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Solubility
Chemical Name/SMILES	(E)-3-(4-(naphthalen-1-yl)phenyl)acrylic acid

参考文献

1. Guang Ren, et al. Diabetes. 2020 Sep;69(9):2003-2016.

UAB126 (UAB 126)

生物&药学活性

物理化学性质&存储条件

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UAB126 (UAB 126)

生物&药学活性

物理化学性质&存储条件

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