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首页-小分子抑制剂&激动剂-Others-Other Targets-U73343
U73343

Chemical Structure : U73343

CAS No.: 142878-12-4

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U73343 (U-73343)

货号: PC-27057Not For Human Use, Lab Use Only.

U-73343 (U73343) an inactive analog of phospholipase C (PLC) inhibitor U73122, also is a potent enhancer of oligodendrocyte formation that induces 8,9-unsaturated sterol accumulation by inhibition of cholesterol biosynthesis enzyme sterol 14-reductase, also inhibits cholesterol 25-hydroxylase (CH25H).

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

U-73343 (U73343) an inactive analog of phospholipase C (PLC) inhibitor U73122, also is a potent enhancer of oligodendrocyte formation that induces 8,9-unsaturated sterol accumulation by inhibition of cholesterol biosynthesis enzyme sterol 14-reductase, also inhibits cholesterol 25-hydroxylase (CH25H).

物理化学性质&存储条件

分子量 466.67
分子式 C29H42N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(6-(((8R,9S,13S,14S,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl)amino)hexyl)pyrrolidine-2,5-dione

参考文献

1. Sax JL, et al. ACS Chem Biol. 2021 Jul 16;16(7):1288-1297.

2. Rahman A, et al. ACS Chem Biol. 2026 Jun 12. doi: 10.1021/acschembio.6c00385.

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