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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-U-93631
U-93631

Chemical Structure : U-93631

CAS No.: 152273-12-6

U-93631 (U93631, U 93631)

货号: PC-42225Not For Human Use, Lab Use Only.

U-93631 (U93631) is a potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

U-93631 (U93631) is a potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.
U-93631 induce a rapid, time-dependent decay of GABA-induced whole-cell Cl- currents in recombinant GABAA receptors.

物理化学性质&存储条件

分子量 299.3676
分子式 C17H21N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

Imidazo[1,5-a]quinoxaline-3-carboxylic acid, 4,5-dihydro-4,4-dimethyl-, 1,1-dimethylethyl ester

参考文献

1. Dillon GH, et al. Mol Pharmacol. 1993 Oct;44(4):860-5.

2. Dillon GH, et al. J Pharmacol Exp Ther. 1995 Feb;272(2):597-603.

3. Dillon GH, et al. Br J Pharmacol. 1995 Jun;115(3):539-45.

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