Tunicamycin

Chemical Structure : Tunicamycin

CAS No.: 11089-65-9

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货号: PC-21959Not For Human Use, Lab Use Only.

Tunicamycin is a homologous nucleoside antibiotic and GlcNAc phosphotransferase (GPT) inhibitor, inhibits N-glycosylation and induces ER-stress, inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.

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2 mg	￥1680	In stock
5 mg	￥2980	In stock
10 mg	￥4880	In stock
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100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	718.71
分子式	C30H46N4O16
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-((2S,3R,4R,5R,6R)-2-(((2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-(2-((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)-5-methylhex-2-enamide

参考文献

1. Nonarath HJT, et al. J Antibiot (Tokyo). 2024 Jan 18. doi: 10.1038/s41429-023-00694-z.

2. Hsu JL, et al. Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):373-82.

3. Hou H, et al. Mol Cancer Ther. 2013 Dec;12(12):2874-84.

Tunicamycin

生物&药学活性

物理化学性质&存储条件

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Tunicamycin

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