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Triapine

Chemical Structure : Triapine

CAS No.: 143621-35-6

Triapine (3-AP, PAN-811, OCX191, NSC663249)

货号: PC-42266Not For Human Use, Lab Use Only.

Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity.

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10 mg ¥780 In stock
25 mg ¥1180 In stock
50 mg ¥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity.

物理化学性质&存储条件

分子量 195.2449
分子式 C7H9N5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 47 mg/mL

Chemical Name/SMILES

Hydrazinecarbothioamide, 2-[(3-amino-2-pyridinyl)methylene]-

参考文献

1. Liu MC, et al. J Med Chem. 1992 Oct 2;35(20):3672-7.

2. Cory JG, et al. Biochem Pharmacol. 1994 Jul 19;48(2):335-44.

3. Chen RW, et al. Neuroscience. 2005;135(1):191-201.

4. Finch RA, et al. Biochem Pharmacol. 2000 Apr 15;59(8):983-91.

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