Chemical Structure : Trebananib
货号: PC-38865Not For Human Use, Lab Use Only.
Trebananib (AMG 386) is a first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2.
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Trebananib (AMG 386) is a first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2.
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外观性状 | Solid | |
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Solubility |
10 mM in DMSO |
1. Coxon A, et al. Mol Cancer Ther. 2010 Oct;9(10):2641-51.
2. Mita AC, et al. Clin Cancer Res. 2010 Jun 1;16(11):3044-56.
3. Oliner JD, et al. Invest Ophthalmol Vis Sci. 2012 Apr 24;53(4):2170-80.
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