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首页-抗体和重组蛋白-Other Fusion Proteins-Trebananib
Trebananib

Chemical Structure : Trebananib

CAS No.: 894356-79-7

Trebananib (AMG386)

货号: PC-38865Not For Human Use, Lab Use Only.

Trebananib (AMG 386) is a first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Trebananib (AMG 386) is a first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

参考文献

1. Coxon A, et al. Mol Cancer Ther. 2010 Oct;9(10):2641-51.

2. Mita AC, et al. Clin Cancer Res. 2010 Jun 1;16(11):3044-56.

3. Oliner JD, et al. Invest Ophthalmol Vis Sci. 2012 Apr 24;53(4):2170-80.

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