Trametinib (GSK1120212, JTP-74057) | MEK inhibitor | Probechem Biochemicals

Chemical Structure : Trametinib

CAS No.: 871700-17-3

加入收藏

Trametinib (GSK1120212, JTP74057, JTP-74057)

货号: PC-42774Not For Human Use, Lab Use Only.

Trametinib (GSK1120212, JTP-74057) is a potent and highly specific MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM.

规格	价格	库存
50 mg	￥580	In stock
100 mg	￥880	In stock
500 mg	￥1980	In stock
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Trametinib (GSK1120212, JTP-74057) is a potent and highly specific MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM.
Trametinib exhibits no inhibition on the kinase activities of c-Raf, B-Raf, ERK1/2.

物理化学性质&存储条件

分子量	615.3948
分子式	C26H23FIN5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-

参考文献

1. Gilmartin AG, et al. Clin Cancer Res. 2011 Mar 1;17(5):989-1000.

2. Flaherty KT, et al. N Engl J Med. 2012 Nov 1;367(18):1694-703.

3. Yamaguchi T, et al. Int J Oncol, 2011, 39(1), 23-31.

Trametinib (GSK1120212, JTP74057, JTP-74057)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Trametinib (GSK1120212, JTP74057, JTP-74057)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.