Chemical Structure : Tralokinumab
CAS No.: 1044515-88-9
货号: PC-Ab1054Not For Human Use, Lab Use Only.
Tralokinumab (CAT-354) is an potent and selective IL-13-neutralizing IgG4 monoclonal antibody (mAb). Tralokinumab specifically binds with high affinity to IL-13, inhibiting its interaction with the IL-13 receptor and thereby neutralising the biological activity of the cytokine. Tralokinumab was approved for the treatment of moderate-to-severe atopic dermatitis..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Tralokinumab (CAT-354) is an potent and selective IL-13-neutralizing IgG4 monoclonal antibody (mAb). Tralokinumab specifically binds with high affinity to IL-13, inhibiting its interaction with the IL-13 receptor and thereby neutralising the biological activity of the cytokine. Tralokinumab was approved for the treatment of moderate-to-severe atopic dermatitis.
分子量 | ||
分子式 | Human IgG4P-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Tralokinumab; Adtralza; 1044515-88-9; CAT-354; LP 0162; Interleukin 13 signaling; IL-13 antibody |
1. 1, Antohe I, et al. Expert Opin Biol Ther. 2013 Feb;13(2):323-6. 2, Walsh GM. Curr Opin Investig Drugs. 2010 Nov;11(11):1305-12. 3, Murray LA, et al. Am J Respir Cell Mol Biol. 2014 May;50(5):985-94. 4, May RD, et al. Br J Pharmacol. 2012 May;166(1):177-93.
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