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首页-抗体和重组蛋白-Biosimilar Antibody-Tralokinumab
Tralokinumab

Chemical Structure : Tralokinumab

CAS No.: 1044515-88-9

Tralokinumab (Anti-human IL-13 mAb, human IgG4P-Kappa; CAT-354)

货号: PC-Ab1054Not For Human Use, Lab Use Only.

Tralokinumab (CAT-354) is an potent and selective IL-13-neutralizing IgG4 monoclonal antibody (mAb). Tralokinumab specifically binds with high affinity to IL-13, inhibiting its interaction with the IL-13 receptor and thereby neutralising the biological activity of the cytokine. Tralokinumab was approved for the treatment of moderate-to-severe atopic dermatitis..

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1 mg ¥3580 In stock
5 mg ¥7580 In stock
10 mg ¥12800 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Tralokinumab (CAT-354) is an potent and selective IL-13-neutralizing IgG4 monoclonal antibody (mAb). Tralokinumab specifically binds with high affinity to IL-13, inhibiting its interaction with the IL-13 receptor and thereby neutralising the biological activity of the cytokine. Tralokinumab was approved for the treatment of moderate-to-severe atopic dermatitis.

物理化学性质&存储条件

分子量
分子式 Human IgG4P-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Tralokinumab; Adtralza; 1044515-88-9; CAT-354; LP 0162; Interleukin 13 signaling; IL-13 antibody

参考文献

1. 1, Antohe I, et al. Expert Opin Biol Ther. 2013 Feb;13(2):323-6. 2, Walsh GM. Curr Opin Investig Drugs. 2010 Nov;11(11):1305-12. 3, Murray LA, et al. Am J Respir Cell Mol Biol. 2014 May;50(5):985-94. 4, May RD, et al. Br J Pharmacol. 2012 May;166(1):177-93.

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