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Tpm1.8/9-1

Chemical Structure : Tpm1.8/9-1

CAS No.: 883542-35-6

Tpm1.8/9-1 (Tpm1.8/9 inhibitor 1, PubChem CID 6494468)

货号: PC-21809Not For Human Use, Lab Use Only.

Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy.
Tpm1.8/9-1 does not affect Tpm1.6/7 or Tpm1.8/9 expression at either the RNA or protein level.
Tpm1.8/9-1 dramatically reduced Wnt/β-catenin signaling.

物理化学性质&存储条件

分子量 188.27
分子式 C12H16N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(2-Methyl-indol-1-yl)-propylamine

参考文献

1. Tong Xu, et al. Cell Death Differ. 2024 Feb 16. doi: 10.1038/s41418-024-01267-9.

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