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首页-抗体和重组蛋白-Biosimilar Antibody-Toripalimab
Toripalimab

Chemical Structure : Toripalimab

CAS No.: 1924598-82-2

Toripalimab (Anti-human PD-1 mAb, human IgG4P-Kappa; JS 001; SO-001; TAB-001)

货号: PC-Ab1103Not For Human Use, Lab Use Only.

Toripalimab (JS 001, SO-001, TAB-001) is an anti-PD-1 monoclonal antibody developed for its ability to block PD-1 interactions with its ligands, PD-L1 and PD-L2, and for enhanced receptor endocytosis function. Blocking PD-1 interactions with PD-L1 and PD-L2 is thought to recharge the immune system’s ability to attack and kill tumor cells..

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1 mg ¥3580 In stock
5 mg ¥7580 In stock
10 mg ¥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Toripalimab (JS 001, SO-001, TAB-001) is an anti-PD-1 monoclonal antibody developed for its ability to block PD-1 interactions with its ligands, PD-L1 and PD-L2, and for enhanced receptor endocytosis function. Blocking PD-1 interactions with PD-L1 and PD-L2 is thought to recharge the immune system’s ability to attack and kill tumor cells.

物理化学性质&存储条件

分子量
分子式 Human IgG4P-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Toripalimab; JS 001; SO-001; TAB-001; Terepril monoclonal antibody; Treipril monoclonal antibody; Treprizumab; Treprizumab; 1924598-82-2; Tripleitriumab; Triprizumab; Anti-human programmed death receptor-1; Anti-human PD1

参考文献

1. 1, Tang B, et al. J Hematol Oncol. 2019 Jan 14;12(1):7. 2, Liu H, et al. MAbs. 2019 May/Jun;11(4):681-690.  3, Sheng X, et al. J Clin Oncol. 2019 Nov 10;37(32):2987-2999.

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