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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Gap Junction Protein-Tonabersat
Tonabersat

Chemical Structure : Tonabersat

CAS No.: 175013-84-0

Tonabersat (SB-220453, SB220453)

货号: PC-21795Not For Human Use, Lab Use Only.

SB-220453 (Tonerbasat) is a potential antimigraine agent and gap-junction modulator, demonstrates activity as a gap-junction inhibitor in animal studies.

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5 mg ¥1480 In stock
10 mg ¥2280 In stock
25 mg ¥3680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SB-220453 (Tonerbasat) is a potential antimigraine agent and gap-junction modulator, demonstrates activity as a gap-junction inhibitor in animal studies.

物理化学性质&存储条件

分子量 391.82
分子式 C20H19ClFNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-3-chloro-4-fluorobenzamide

参考文献

1. Chan WN, et al. Bioorg Med Chem Lett. 1999 Jan 18;9(2):285-90.

2. Read SJ, et al. Cephalalgia. 2000 Mar;20(2):92-9.

3. Parsons AA, et al. Br J Pharmacol. 2001 Apr;132(7):1549-57.

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