Toceranib phosphate |CAS:874819-74-6 Probechem Biochemicals

Chemical Structure : Toceranib phosphate

CAS No.: 874819-74-6

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Toceranib phosphate (SU 11654;PHA 291639;SU11654;SU-11654;PHA-291639;PHA291639)

货号: PC-42529Not For Human Use, Lab Use Only.

An ATP-competitive inhibitor of RTKs, including VEGFR, FGFR, PDGFR, and Kit.

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50 mg	￥3680	In stock
100 mg	￥6580	In stock
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生物&药学活性

An ATP-competitive inhibitor of RTKs, including VEGFR, FGFR, PDGFR, and Kit; inhibits phosphorylation of WT Kit in the presence of stem cell factor at concentrations as low as 0.01 uM; disrupts function of all forms of mutant Kit in cells.

物理化学性质&存储条件

分子量	494.4531
分子式	C22H28FN4O6P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrrole-3-carboxamide, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-, phosphate (1:1)

参考文献

1. Liao AT, et al. Blood. 2002 Jul 15;100(2):585-93.

2. London CA, et al. Clin Cancer Res. 2003 Jul;9(7):2755-68.

3. London C, et al. Vet Comp Oncol. 2012 Sep;10(3):194-205.

Toceranib phosphate (SU 11654;PHA 291639;SU11654;SU-11654;PHA-291639;PHA291639)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

Toceranib phosphate (SU 11654;PHA 291639;SU11654;SU-11654;PHA-291639;PHA291639)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

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