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首页-新冠病毒相关-SARS-CoV-2 Antibodies-Tixagevimab
Tixagevimab

Chemical Structure : Tixagevimab

CAS No.: 2420563-99-9

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Tixagevimab (AZD8895)

货号: PC-38879Not For Human Use, Lab Use Only.

Tixagevimab (AZD8895) is a monoclonal antibody (mAb) against the SARS-CoV-2 spike protein, binds to distinct, nonoverlapping epitopes on the spike protein receptor binding domain to neutralize SARS-CoV-2, used in a combination of Tixagevimab/cilgavimab (AZD7442).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Tixagevimab (AZD8895) is a monoclonal antibody (mAb) against the SARS-CoV-2 spike protein, binds to distinct, nonoverlapping epitopes on the spike protein receptor binding domain to neutralize SARS-CoV-2, used in a combination of Tixagevimab/cilgavimab (AZD7442).

Isotype: IgG1-kappa.
Anti-[human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], human monoclonal antibody.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. VanBlargan LA, et al. Nat Med. 2022 Mar;28(3):490-495.

2. Loo YM, et al. Sci Transl Med. 2022 Mar 9;14(635):eabl8124.

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